Antioxidants & Anti-Aging Substance for HEALTH

European Journal of Clinical Nutrition (2007) 61, 295–303. doi:10.1038/sj.ejcn.1602510; published online 16 August 2006

Age and the Changing Body

If you ask people, most will tell you they do not want to grow old. However, the aging of the body as we enter into our later years is an inescapable reality of life. From the moment we are born until we fully mature around our early twenties, our bodies are in a constant and progressive stage of development. From our mid-twenties forward, our bodies will remain at a constant level and continue to repair those areas that have deteriorated. The body’s hormones will also begin changing. If one does not take proper care of one’s health, the body will more or less begin to deteriorate; depending on each individual. As we approach the age of 30-40 and older, the body will begin to experience a decrease in hormone production. By middle age and onwards the body will begin to exhibit clear physical signs of aging.

Key Indicators of Aging

Some key indicators of aging are the appearance of wrinkles, sagging skin, uneven skin tone, age spots, loss of elasticity in skin, slowing metabolism, thinning hair, balding, and receding hairline. People also experience a decrease in muscle mass and bone density, decrease in the flexibility of the tendons muscles and joints, body aches and pains, and slower reflexes; leading to less precision in movement,
a decline in physical dexterity, and decrease in strength and ability to carry out physical tasks. Some may also experience decreasing mental clarity and sharpness.

In addition to this, people develop a greater risk and higher rate of developing chronic diseases; such as heart conditions, high blood pressure, diabetes, cancer, etc.; the severity and instance of which varies from person to person, depending level of health.

How does premature aging occur?

Medical doctors across the world agree that the deterioration of the body is due, in no small part, to damage caused by free radicals. Free radicals are atoms or group of atoms with an unpaired number of electrons. This lack of a pair makes them unstable and causes them to grab electrons from the atoms of nearby cells or molecules. Losing an electron to the free radical causes the cell or molecule to become an unstable free radical itself, thereby causing a chain reaction. This can lead to widespread cellular damage and inhibits the ability of the damaged cells to function properly. Consequently, extensive free radical damage to cell DNA can lead to mutations and abnormalities in cell division that can cause cancer.

What is Anti-Aging?

Most people understand anti-aging as the delaying of the aging process or retaining of youth. Often times the emphasis is on the youthful appearance of the face. In medical terms, however, anti-aging refers to extending one’s longevity or life. There is a desire for a longer and higher quality of life. This also includes delaying the deterioration of the body and reducing the risk/rate of contracting various illnesses and diseases in older age. Anti-aging extends to the improvement of mental health as well. Anti-aging covers the gamut of maintaining the quality, care, and proper functioning of the body; and delaying the body’s natural process of degeneration.

Types of Free Radicals and Antioxidants

There are two types of Free Radicals:
1. External/Environmental: pollution, pesticides, cigarette smoke, UV radiation, synthetic substances
2. Internal: natural byproduct of metabolism, stress/anxiety

Antioxidants are molecules that combat free radicals and help protect against cell and tissue damage caused by oxidation. Antioxidants can be put into two categories.
1. Internal antioxidants produced by the body- various enzymes including catalyst, glutathione, superoxide dismutase, etc.
2. External antioxidants cannot be produced by the body. These antioxidants come from diet and nutrition. These include isoflavones, bioflavonoids, Coenzyme Q10, vitamin C, vitamin E, etc.

How can we slow down the aging process?

1. Consuming beneficial foods
Maintaining a balanced and nutritious diet is the benchmark of good health. But how many people actually put in the effort of including foods from all five food groups and the correct number of servings in their diet every day? Our fast paced hectic modern lifestyles make it all too easy for us to replace balanced nutritious meals with fast, convenient, heavily processed junk foods. These foods are often full of refined sugars, starchy carbohydrates, and saturated or trans fatty acids. Therefore consuming junk food is harmful to our health and their accumulation in the body can lead to obesity, diabetes, high cholesterol, high blood pressure, strokes, and increased risk of developing cancer. An insufficient nutritive diet combined with the oxidative stress and free radical damage will cause one to age faster. Clear signs of this can be the destruction of the collagen structure in the dermis which makes the skin saggy, wrinkled, and marked with age spots. All of this contributes to making you look much older than you actually are.

2. Regular Exercise

Regular exercise is crucial to optimum health and wellbeing. Exercise increases blood circulation and flexibility, especially in the joints and muscles. Exercise can increase bone mass and increase HDL (good) cholesterol while decreasing LDL (bad) cholesterol, thereby reducing risk of heart attack and stroke. During sustained exercise the body also releases endorphins (hormone) that helps to reduce stress and cause you to feel happy. The important thing to consider is the type of physical exercise you engage in, ensuring that it is appropriate for your physical condition and age. To receive the full benefits of exercise you should exercise thirty minutes 3-4 times a week.

3. Adequate Sound and Restful Sleep

Getting adequate sleep every day is crucial for the body to heal and repair itself from the stresses of the day. When asleep, the body repairs and recovers all of the cells in the body. It is important that people get 6-8 hours of sleep each night. It is also important to reduce stress, because stress is another crucial factor that can lead to aging. People should have a creative and positive outlook on life and in the way they live. You need to know how to encourage and motivate others and to give them compliments. This not only brings happiness to others but also brings peace and happiness to yourself. One should meditate to relax and focus the mind everyday. Those who receive adequate good quality sleep, are stress free, and have a positive attitude will age slower and be more youthful. You can be on those people and you will look fresh and vibrant, someone that others want to be around.

4. Avoid or Reduce Exposure to Free Radicals

Exposure to Free Radicals is a crucial factor in contributing to rapid aging. Therefore it is prudent to limit your exposure to free radicals; such as those caused by smoking, alcohol, stress, pickled foods, smog and chemical pollution,
and UV Radiation.

5. Increase consumption of Antioxidants

Even though the body produces its own array of antioxidants, they are not enough to combat the amount of free radicals and oxidative stress the body is subjected to these days. It is therefore necessary to increase your intake of antioxidants by consuming antioxidant super foods and other nutritional/dietary supplements with the adequate amount of antioxidants and phytochemicals.

6. Increase intake of crucial nutrients and vitamins for the body’s structure

As the body changes with age, as was explained in the beginning, it is partly the result of changes to the body’s internal molecular structure, known as collagen. Collagen is a protein that makes up about 25% of the bodies total protein and is the primary component of connective tissue in the body. Collagen is found in skin tissue, bones, cartilage, ligaments, arteries, cornea, walls of the uterus, muscles, liver, lungs, etc. Collagen is constantly being torn down and rebuilt and repaired. The changing of the body in old age causes the body to not produce enough collagen. This leads to decline in the body’s performance, flexibility in the joints, bones, and muscles; causing the body to not function as well as in the past. The skin begins to wrinkle, sag, and lose its elasticity. It is therefore important to take collagen supplements to delay and mitigate the effects of aging, and to prolong a more robust and youthful life even in one’s later years.

Dermarine fills in the gap where nutrition, sleep, and exercise are no longer enough to minimize and delay the effects of aging. Combining some of the most potent and beneficial antioxidants together in one tablet, Dermarine is the answer to a more vitalized and youthful you. Below is a list of Dermarine’s active ingredients, all coming from the highest quality sources.
Potent and Approved Popular Antioxidants

Vitamin E

Vitamin E is a potent and essential antioxidant that provides free radical protection to cell walls. Vitamin E also contributes to the production of collagen in the skin. Vitamin E protects against the premature formation of wrinkles. Vitamin E also boosts the immune system’s ability to ward off dementia and helps to protect against the mutation of cells that leads to cancer. Vitamin E has the effect of slowing down all the signs of aging that occur on, and within, the body.


Zinc is an essential mineral that is vital to proper cellular function. Zinc has an important role in synthesizing nucleic acid and over 100 various enzymes. Zinc helps boost the immune system, protect against cancer, maintain proper sense of taste, smell, and vision, speeds up healing, protects against balding, promotes the body’s production of antibodies, reduces inflammation, and helps counter the effects of rheumatoid arthritis.


Selenium is a trace mineral that is essential to the formation of various antioxidant enzymes in the body. Selenium helps to boost the immune system, protects the skin, and increases elasticity in the skin. Having the correct amount of selenium in the system can help the skin look more radiant and youthful while retaining moisture and minimizing the appearance of fine lines and wrinkles.


Lycopene is a carotenoid phytochemical found in tomatoes and certain other red/orange fruits. Lycopene has an antioxidant capacity up to 100 times greater than that of Vitamin E. Lycopene is a highly beneficial antioxidant that should not be missing from one’s diet. Lycopene protects cells from degradation, prevents the formation of wrinkles, and makes the skin bright and fresh.

Collagen Peptides

Collagen peptides are a type of small molecule collagen that, because of its small molecular size, is easily absorbed into the body. Collagen peptides make the body stronger and add resilience and flexibility to the existing collagen throughout the dermis. This has the benefit of making the skin firm, reducing the appearance of wrinkles, and increasing flexibility and strength in the joints, ligaments, and tendons; reducing inflammation in the joints and making them more mobile. This is especially beneficial to seniors.


Phytosterols are a group of potent antioxidants. Phytosterols are anti-inflammatory and help with infection. Phytosterols also protect the skin from UV Radiation damage from the sun while at the same time helping the skin retain moisture. Phytosterols are an important antioxidant in preventing the premature wrinkling of the skin. And because it is a potent antioxidant, it has the ability to combat free radical damage in the body, contributing to the prevention of cancer.

Shark Cartilage Extract

Shark Cartilage Extract is comprised of glucosamine, collagen, and chondroitin sulfate. Shark cartilage extract helps to strengthen and fortify collagen in the skin, making the skin more elastic and resilient. It can also help reduce inflammation in the joints that many seniors experience. Mucopolysaccharide is a constituent in shark cartilage extract and has the benefit of suppressing the formation of new blood vessels in cancerous cells and tumors, inhibiting the spread of these cells; particularly uterine, prostate, and breast cancers.


Hesperidin is classified as a flavonone glycoside, and can be found in citrus fruits. It is an antioxidant, is anti-inflammatory, reduces cholesterol (lipolipedemic), is anti-carcinogenic, and strengthens the veins (vasoprotective) thereby helping to reduce vascular permeability. A lack of hesperidin in the body can lead to fatigue, nighttime leg cramping, and abnormalities and improper functioning in the capillaries.


Isoflavones, a phytoestrogen, is an antioxidant found in soy germ extract. It is popular for the treatment of various ailments for seniors. It replaces the need for taking artificial synthetic hormones. Isoflavones can prevent the development of osteoporosis as well as have the ability to protect the DNA from free radical damage. Isoflavones help divert the transportation of nutrients to cancer cells while helping to reduce the development of cancers and tumors.

Co-Enzyme Q10 or Co-Q10

Co-Q10 has an important role in the production of energy by mitochondria within cells. Co-Q10 improves and restores the functioning of cells. Co-Q10 can increase the energy levels of cells in the heart, making the heart function more efficiently.
A stronger heart can pump the blood better, reducing blood pressure. Co-Q10 also has an antioxidant effect in regards to boosting the immune system and combating free radical damage that can lead to the formation of cancer. Co-Q10 also helps
to reduce the deterioration of skin and prevents the formation of wrinkles, while increasing the energy levels of skin cells. Co-Q10 effectively speeds up the process of restoration and rejuvenation of skin cells.


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